Next Generation Integrative Genomics

Strategic theme directors :

Jacques Simard, Ph.D., Université Laval
Vincent Ferretti, Ph.D., Université de Montréal - CHU Sainte-Justine
John Rioux, Ph.D., Université de Montréal - Institut de Cardiologie de Montréal

Next generation sequencing (NGS) is a new technology that allows all individual genetic variations to be captured through massively parallel sequencing microarrays. This promises to revolutionize the role of genetic variation in disease prediction and prevention, and response to therapy – the new era of personalized medicine. Despite the rapid progress of NGS technologies, there remains a large gap between the production of sequence and the ability to compile, analyze and interpret the resulting data. To fill this gap and enable researchers to access and benefit from these new technologies, this new Strategic Theme aims to develop specialized bioinformatics tools and NGS analysis paradigms to interpret genetic variation, and offer this expertise to RMGA researchers and the scientific community.

Sequencing facilityExome capture, NGS sequencingDaniel Sinnett
NGS study designConsultation on NGS study design and analysis strategiesDaniel SinnettJacques Simard,Guy Rouleau
NGS dataset analysisFee-for-service analysis of NGS datasets, development of bioinformatics analysis toolsDaniel SinnettJacques Simard,Guy Rouleau